Cheap flights from Panama City to Santa Cruz de la Sierra (PTY–VVI)
Panama
Bolivia
Boliviana de Aviación and Copa Airlines fly Panama City to Santa Cruz de la Sierra (PTY–VVI) nonstop and back, a great-circle distance of 3,470 km (2,150 mi).
- From
- PTY
- Panama City
- To
- VVI
- Santa Cruz de la Sierra
- Nonstop
- Yes · 2 airlines
- Airlines
- OB · CM
- Cheapest fare found
- $510 one-way
- Distance
- 3,470 km (2,150 mi)
- Time difference
- Santa Cruz de la Sierra 1 hour ahead
Network data imported from airport and airline sources:· How we verify
Panama City to Santa Cruz de la Sierra fares by month
Cheapest one-way fare found: $510 for July 2027 on Copa Airlines (1 stop).
- Jul ’27$510
Cheapest one-way fares per month of departure in the Aviasales price cache, found . Fares change by the hour: the live fare is shown when you search.
When to fly PTY–VVI
Days in Santa Cruz de la Sierra average 18–28 °C in May, June and July. Set your watch 1 hour forward on landing at VVI.
Panama City to Santa Cruz de la Sierra: frequently asked questions
Fares: Aviasales price cache, 8 October 2026.
How much is a flight from Panama City Tocumen (PTY) to Santa Cruz de la Sierra Viru Viru (VVI)?
From $510 one-way, the cheapest fare found for July 2027 on Copa Airlines with 1 stop (found 8 October 2026).
Which airlines fly PTY–VVI direct?
Boliviana de Aviación and Copa Airlines.
What is the time difference between Panama City and Santa Cruz de la Sierra?
Santa Cruz de la Sierra is 1 hour ahead of Panama City: a PTY departure at noon is 13:00 local time in VVI.
Santa Cruz de la Sierra to Panama City: the return flight (VVI–PTY)
All 2 airlines also fly VVI–PTY nonstop.
Airlines flying PTY–VVI nonstop
| Airline | Usually takes off (PTY time) | Type | Alliance | Notes |
|---|---|---|---|---|
 Boliviana de Aviación OB | — | full-service | — | — |
 Copa Airlines CM | — | full-service | Star Alliance | — |
One-stop alternatives to flying PTY–VVI nonstop
One airline on both legs; check it's sold as one ticket.
- Via Bogotá (BOG) with
Avianca: 3,520 km (2,190 mi) flown, 2% further than nonstop.
PTY–VVI route map
More from Panama City and Santa Cruz de la Sierra
Explore the airlines’ route maps
Departure
Tocumen International Airport
Tocumen (PTY), Panama City. In our data, 22 airlines fly nonstop from PTY to 91 destinations.
View PTY airport guide →Arrival
Viru Viru International Airport
Viru Viru (VVI), Santa Cruz de la Sierra.
Weather in Santa Cruz de la Sierra vs Panama City
Santa Cruz de la Sierra is warmer than Panama City in 0 months and cooler in 8; the biggest gap is in June (26°C against 32°C). In October it averages 32°C in Santa Cruz de la Sierra and 31°C in Panama City.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Santa Cruz de la Sierra | 31° | 31° | 31° | 29° | 27° | 26° | 26° | 29° | 31° | 32° | 32° | 31° |
| Panama City | 32° | 33° | 33° | 33° | 32° | 32° | 32° | 32° | 31° | 31° | 31° | 32° |
Average daily highs. Climate normals from Santa Cruz de la Sierra and Panama City (Wikipedia, CC BY-SA), which cite the national weather services.
Onward from Santa Cruz de la Sierra
Places you can't fly to nonstop from PTY, but can from VVI — for a stopover or a second leg.
Related routes
Sources
- en.wikipedia.org — airlines and destinations, checked 2026-10-01
- en.wikipedia.org — airlines and destinations, checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
- en.wikipedia.org — airlines and destinations table (passenger), checked 2026-10-01
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